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When Harrison moved to the Executive Mansion, so did his father-in-law, John Scott, a Presbyterian minister, who each day at breakfast opened up the meal with prayer. Completely absorbed with his trust in the Lord, Harrison issued a record number, eight, of proclamations for national days of thanksgiving and prayer between 1889 and 1891.
As his first term was coming to an end, he was accused of using his prayer proclamations for political advantage. This was a setback to him and he refrained to do so from then on. During his reelection battle, his wife, Caroline, was fighting TB. She died just two weeks before the election. He credited prayer with keeping him afloat both spiritually and emotionally during this time of losing her and of being defeated at the polls.